Nowadays global inequalities in access to vaccines seem to be a growing problem. Intellectual Property Rights have been playing an important role both in causing and worsening them. Firstly,...

The ontological question goes way back to Plato. In his Teetetus he already searched for the answer to question of “how is it possible that when a man stares at something he would not see anything anyway”. Quine is the author of a doctrine on ontology, “On what there is”. His work follows the path of medieval authors such as William of Ockham, who proposed the methodology that came to be known as Okcham's razor. The excessive proliferation of entities is (...) known as “Plato's beard”. Quine, among others, has shaved Plato's beard searching for logical and scientific simplicity. (shrink)

Los debates sobre el conocimiento, la realidad y la verdad han estado en el centro de la discusión filosófica desde hace décadas. El advenimiento de la Teoría Evolucionista del Conocimiento le ha revestido, no solo de hipótesis interesantes sobre los procesos que subyacen a las capacidades cognitivas en la tarea de conocer el mundo, sino que ha traído consigo nuevos problemas. En este artículo se intenta ofrecer una perspectiva naturalizada del problema del conocimiento, adentrándonos en los debates suscitados desde el (...) realismo y los conceptos de verdad y error a la hora de determinar si el éxito biológico está íntimamente relacionado o no con ambos conceptos, no solo en la especie humana sino también en otras especies animales. (shrink)

El presente artículo tiene por objetivo realizar un análisis del quehacer del profesional y especialista de seguridad y salud en el Trabajo de un grupo egresados de esta disciplina, este proceso parte del análisis de cuatro dimensiones, una primera enfocada a la parte demográfica, la segunda lo sociolaboral, la tercera a las barreras que se pueden presentar en la Gestión de Seguridad y Salud en el Trabajo en las empresas y la cuarta enfocada en aspectos tecnológicos y de innovación en (...) el diseño, implementación y mantenimiento del Sistema de Gestión de Seguridad y Salud en el Trabajo. (shrink)

From a scientific standpoint, the world is more prepared than ever to respond to infectious disease outbreaks; paradoxically, globalization and air travel, antimicrobial resistance, the threat of bioterrorism, and newly emerging pathogens driven by ecological, socioeconomic, and environmental factors, have increased the risk of global epidemics.1,2,3 Following the 2002–2003 severe acute respiratory syndrome (SARS), global efforts to build global emergency response capabilities to contain infectious disease outbreaks were put in place.4,5,6 But the recent H1N1, Ebola, and Zika global epidemics have (...) shown unnecessary delays and insufficient coordination in response efforts.7,8,9,10 In a thoughtful and compelling essay,11 Thana C. de Campos argues that greater clarity in the definition of pandemics would probably result in more timely effective emergency responses, and pandemic preparedness. In her view, a central problem is that the definition of pandemics is based solely on disease transmission across several countries, and not on spread and severity together, which conflates two very different situations: emergency and nonemergency disease outbreaks. A greater emphasis on severity, such that pandemics are defined as severe and rapidly spreading infectious disease outbreaks, would make them “true global health emergencies,” allowing for priority resource allocation and effective collective actions in emergency response efforts. Sympathetic to the position taken by de Campos, here I highlight some of the challenges in the definition of severity during an infectious disease outbreak. (shrink)

The main idea that we want to defend in this paper is that the question of what a logic is should be addressed differently when structural properties enter the game. In particular, we want to support the idea according to which it is not enough to identify the set of valid inferences to characterize a logic. In other words, we will argue that two logical theories could identify the same set of validities, but not be the same logic.

The facultative intracellular pathogen Salmonella enterica serovar Typhimurium faces multiple environments during infection, including different cell types as well as extracellular fluids. We propose that Salmonella ascertains its cellular location by assessing the Mg2+ concentration of its milieu. A signal transduction system, PhoP/PhoQ, signals Salmonella its presence in a intracellular (low Mg2+) or extracellular (high Mg2+) environment, thereby promoting transcription of genes required for survival within or entry into host cells. The PhoP/PhoQ system is high in a regulatory hierarchy that (...) controls other signal transduction systems that respond to different host cues, enabling the microorganism to determine its precise tissue and cellular location. BioEssays 20:96–101, 1998. © 1998 John Wiley & Sons, Inc. (shrink)

Horizontal gene transfer advances bacterial evolution. To benefit from horizontally acquired genes, enteric bacteria must overcome silencing caused when the widespread heat‐stable nucleoid structuring (H‐NS) protein binds to AT‐rich horizontally acquired genes. This ability had previously been ascribed to both anti‐silencing proteins outcompeting H‐NS for binding to AT‐rich DNA and RNA polymerase initiating transcription from alternative promoters. However, we now know that pathogenic Salmonella enterica serovar Typhimurium and commensal Escherichia coli break down H‐NS when this silencer is not bound to (...) DNA. Curiously, both species use the same protease – Lon – to destroy H‐NS in distinct environments. Anti‐silencing proteins promote the expression of horizontally acquired genes without binding to them by displacing H‐NS from AT‐rich DNA, thus leaving H‐NS susceptible to proteolysis and decreasing H‐NS amounts overall. Conserved amino acid sequences in the Lon protease and H‐NS cleavage site suggest that diverse bacteria degrade H‐NS to exploit horizontally acquired genes. (shrink)

The origins and development of the problem of mental causation are outlined. The underlying presuppositions which give rise to the problem are identified. Possible strategies for solving, or dissolving the problem are examined.

Esta sección temática constituye la segunda discusión sobre el desafío de la adopción de reglas lógicas publicado en Análisis Filosófico. Al igual que la primera, esta colección de artículos puede verse como el resultado de la colaboración internacional que durante más de dos décadas hemos mantenido entre el Saul Kripke Center (SKC) y el IIF-SADAF-CONICET. Y más precisamente, entre Saul, Romina y el grupo de lógica de Buenos Aires (BA-Logic). Visitas, seminarios, workshops, proyectos internacionales, y fundamentalmente mucho afecto y pasión (...) por los problemas filosóficos fundamentales han marcado este proceso. Tanto Romina como Saul han apoyado sistemáticamente los esfuerzos desde Argentina para producir conocimiento en el área de lógica. Ambos han estado involucrados no solo institucionalmente en el apoyo al desarrollo de nuestro grupo, sino también a nivel personal. Fueron muchos los momentos que compartimos juntos. Muchos recuerdos e historias. Es importante destacar, solo para mencionar un simple aspecto de nuestras historias comunes, que Saul participó activamente en el proceso de elaboración de la propuesta de ambos números, en la lectura de gran parte del material, e incluso como réferi de algunos trabajos. Saul y Romina asistieron por Zoom a varias reuniones en el marco de los seminarios que generaron parte del material aquí publicado. Recuerdo la alegría de Saul, sus comentarios y la sorpresa de muchos de los participantes de ver aparecer en sus pantallas al filósofo más importante del mundo y uno de los más importantes de la historia. Para ellos quizás era Kripke, para mi ya era Saul. Nos hubiera gustado celebrar juntos. Podría haber sido en Buenos Aires o en Nueva York. Lamentablemente, ya no podrá ser. Aunque también es cierto que esta sección temática es una manera de volver a reunirnos y de expresar el profundo agradecimiento que todos los integrantes del BA-Logic tenemos por Saul. Te vamos a extrañar… Ya te estamos extrañando…. (shrink)

The global economy’s centre of gravity is shifting. Emerging and developing countries have been contributing over 50% of the global GDP since the onset of the 21st century, which is unprecedented since the Industrial Revolution. This article offers the first analysis of the creeping convergence of the BRIC world (ie Brazil, Russia, India and China) with global legal standards in a key area of International Law: the International Tax Regime (ITR). The ITR is a legal technology fundamentally designed by the (...) League of Nations in the 1920s, when the BRICs played no relevant role. This article proposes a theory that aims to illuminate the core driving forces of the on-going trend towards global convergence in this area of International Law from both the static and dynamic dimensions. It is grounded on the logic of two-sided platforms. (shrink)

What accounts for the apocalyptic angst that is now so clearly present among Americans who do not subscribe to any religious orthodoxy? Why do so many popular television shows, films, and music nourish themselves on this very angst? And why do so many artists—from Coldplay to Tori Amos to Tom Wolfe—feel compelled to give it expression? It is tempting to say that America’s fears and anxieties are understandable in the light of 9/11, the ongoing War on Terror, nuclear proliferation, and (...) the seemingly limitless capacity of science to continually challenge our conceptions of the universe and ourselves. Perhaps, too, American culture remains so permeated by Protestant Christianity that even avowed skeptics cannot pry themselves from its grip. In _A Consumer’s Guide to the Apocalypse,_ Eduardo Velásquez argues that these answers are too pat. Velásquez’s astonishing thesis is that when we peer into contemporary artists’ creative depiction of our sensibilities we discover that the antagonisms that fuel the current cultural wars stem from the same source. Enthusiastic religions and dogmatic science, the flourishing of scientific reason and the fascination with mystical darkness, cultural triumphalists and multicultural ideologues are all sustained by the same thing: a willful commitment to the basic tenets of the Enlightenment. Velásquez makes his point with insightful readings of the music of Coldplay, Tori Amos, and Dave Matthews and the fiction of Michael Frayn’s _Copenhagen,_ Chuck Palahniuk’s _Fight Club,_ and Tom Wolfe’s _I Am Charlotte Simmons._ Written with grace and humor, and directed toward the lay reader, _A Consumer’s Guide to the Apocalypse_ is a tour de force of cultural analysis. (shrink)

In this paper I criticize Comesaña's point of view on Putnam's model-theoretic argument. I claim that there is an interesting point made by the argument that Comesaña has not taken into account: if we want our semantic assertions to be at ali justified, the externalist claim according to which justification requires the God 's Eye View has to be given up.

In his article “The Status of Content”, Boghossian defends what has been called “trascendentalism about content”. According to him, the thesis that there is nothing in the world that corresponds to our thoughts “is not merely implausible but incoherent”. In other words, he thinks that the thesis in question is not simply false on empirical basis but rather self-refuting or pragmatically incoherent. My purpose in this article is to show that Boghossian´s argument for his point of view is not valid. (...) My main thesis is that there is no contradiction in applying the notion of truth to both semantical and psychological sentences and, at the same time, holding that there are neither semantic nor mental contents. (shrink)

El objetivo de este artículo es evaluar la importancia de los líderes africanos en la política exterior de sus países. A partir de una revisión comprehensiva de literatura especializada, se evidencia la intrascendencia en África de los marcos teóricos tradicionales del análisis de política exterior, los cuales se basan principalmente en la experiencia diplomática de las grandes potencias. En el contexto de los países africanos, por el contrario, la unidad decisoria final no está institucionalizada, por lo cual la visión de (...) mundo de los líderes se transforma en prácticamente la única referencia para la fijación de la estrategia internacional y el interés nacional. (shrink)

In this article I analyze the class- and cultural-based exclusion produced by the Chilean neoliberal educational reform, carried out during the period from 1990 to 2010. This educational reform follows the same neoliberal model applied to the economy of the country. Although some indicators improved in relation to coverage and public spending in education, the performance gap among social groups increased. In addition, at a cultural level, the reform promoted the value of individual productivity negatively affecting some of the cultural (...) behaviors developed by low-income groups as a consequence of and as reaction to the exclusion they suffer. Namely, by stressing the notions of human capital and quality education, the reform has tended to reinforce these students? fatalism, and limit the scope of the organizations they form to improve their academic and social opportunities. (shrink)

In this article I study Kant's doctrine of the power of judgement. I focus on its main function of rendering possible the transition from the lawfulness of nature to the realization of practical ends. In order to do so, I analyze the concept of “spontaneity” and the principle of “purposiveness of nature”, understood as a “principle of contingency”, according to Kant's explanation in the Critique of the Power of Judgement.

¿Podemos adoptar una regla de inferencia como si fuera una hipótesis e inferir algo en virtud de esa regla? ¿Podemos revisar nuestras reglas y principios lógicos en virtud de la evidencia disponible? El antiexcepcionalismo lógico desafía la idea de que la lógica es excepcional y la vincula con el resto de las teorías científicas. Sin embargo, el desafío de la adopción planteado por Kripke y Padró imponen límites a esta concepción. En esta sección, se exploran distintos aspectos vinculados a la (...) imposibilidad de adoptar reglas, el antiexcepcionalismo, la revisión y la normatividad de la lógica. (shrink)

¿Seguimos reglas de inferencia al razonar? Por más intuitiva que resulte la respuesta positiva a esta pregunta, hay una serie de dificultades para vincular reglas lógicas y prácticas inferenciales. El Problema de la Adopción de Reglas de Inferencia constituye un desafío para todo aquel que proponga que podemos seguir nuevos patrones inferenciales a partir del reconocimiento de reglas. En esta sección temática se exploran diversos asuntos conectados a si podemos seguir un nuevo patrón inferencial en virtud de una regla.

Feedback loops have been identified in a variety of regulatory systems and organisms. While feedback loops of the same type (negative or positive) tend to have properties in common, they can play distinctively diverse roles in different regulatory systems, where they can affect virulence in a pathogenic bacterium, maturation patterns of vertebrate oocytes and transitions through cell cycle phases in eukaryotic cells. This review focuses on the properties and functions of positive feedback in biological systems, including bistability, hysteresis and activation (...) surges. BioEssays 30:542–555, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

This book is a collection of secondary essays on America's most important philosophic thinkers—statesmen, judges, writers, educators, and activists—from the colonial period to the present. Each essay is a comprehensive introduction to the thought of a noted American on the fundamental meaning of the American regime.

The present work is motivated by recent experiments aimed to measure the propagation velocity of bound electromagnetic field that reveal no retardation in the absence of EM radiation. We show how these findings can be incorporated into the mathematical structure of special relativity theory that allows us to reconsider some selected problems of classical and quantum electrodynamics. In particular, we come to the conclusion that the total four-momentum for a classical system “particles plus fields” ought to be a present state (...) function of moving charges if EM radiation is negligible. In quantum domain, we analyze novel definition of the momentum operator recently suggested in the study of quantum phase effects. It implies that bound EM field energy and momentum are to be present state functions, too. Being in agreement with reported experiments, these conclusions suggest the necessity to carry out more precise experimental verifications for additional and independent determination of propagation properties of bound EM fields. A scheme of a possible experiment on this subject is also proposed. (shrink)

A theory of magnitudes involves criteria for their equivalence, comparison and addition. In this article we examine these aspects from an abstract viewpoint, by focusing on the so-called De Zolt’s postulate in the theory of equivalence of plane polygons (“If a polygon is divided into polygonal parts in any given way, then the union of all but one of these parts is not equivalent to the given polygon”). We formulate an abstract version of this postulate and derive it from some (...) selected principles for magnitudes. We also formulate and derive an abstract version of Euclid’s Common Notion 5 (“The whole is greater than the part”), and analyze its logical relation to the former proposition. These results prove to be relevant for the clarification of some key conceptual aspects of Hilbert’s proof of De Zolt’s postulate, in his classicalFoundations of Geometry(1899). Furthermore, our abstract treatment of this central proposition provides interesting insights for the development of a well-behaved theory ofcompatiblemagnitudes. (shrink)

In this paper we develop a general representation theory for MV-algebras. We furnish the appropriate categorical background to study this problem. Our guide line is the theory of classifying topoi of coherent extensions of universal algebra theories. Our main result corresponds, in the case of MV-algebras and MV-chains, to the representation of commutative rings with unit as rings of global sections of sheaves of local rings. We prove that any MV-algebra is isomorphic to the MV-algebra of all global sections of (...) a sheaf of MV-chains on a compact topological space. This result is intimately related to McNaughton’s theorem, and we explain why our representation theorem can be viewed as a vast generalization of McNaughton’s theorem. In spite of the language used in this abstract, we have written this paper in the hope that it can be read by experts in MV-algebras but not in sheaf theory, and conversely. (shrink)

Ethnopedology is the study of local knowledge of soil and land management in an ecological perspective. It is an emerging hybrid discipline that is a component of ethnoecology and stands to offer much for land-based studies. This paper reviews the field of ethnopedology in Latin America and compares some of the many case studies from that region. Various literature sources are considered, including the ethnographical, ethnohistorical, archaeological, geographical, agronomic, ethnoecological, and development studies. Our review invokes the theory of ethnoecology that (...) focuses on the linkages between kosmos, corpus, and praxis of local land-users. The main topics covered are the ethnohistorical and archaeological evidence of ethnopedology, local soil and land classification, local land management systems, local perceptions and beliefs of soil and land resources, and local soil fertility management. After analysing past and present research trends, recommendations are given on how ethnopedological studies can contribute to enhance sustainable land use and management in Latin America. (shrink)

In “A new proof of the completeness of the Lukasiewicz axioms” Chang proved that any totally ordered MV-algebra A was isomorphic to the segment \}\) of a totally ordered l-group with strong unit A *. This was done by the simple intuitive idea of putting denumerable copies of A on top of each other. Moreover, he also show that any such group G can be recovered from its segment since \^*}\), establishing an equivalence of categories. In “Interpretation of AF C (...) *-algebras in Lukasiewicz sentential calculus” Mundici extended this result to arbitrary MV-algebras and l-groups with strong unit. He takes the representation of A as a sub-direct product of chains A i, and observes that \ where \. Then he let A * be the l-subgroup generated by A inside \. He proves that this idea works, and establish an equivalence of categories in a rather elaborate way by means of his concept of good sequences and its complicated arithmetics. In this note, essentially self-contained except for Chang’s result, we give a simple proof of this equivalence taking advantage directly of the arithmetics of the the product l-group \, avoiding entirely the notion of good sequence. (shrink)

Open Compositionality: Towards a Methodology of Language offers a fresh view into human languages as supermodular, highly interactive cognitive capacities allowing for human unique thought and communication. It is a novel account of semantics as decision-making in tandem with the cognition first methodology.

We study the algebraizability of the logics constructed using literal-paraconsistent and literal-paracomplete matrices described by Lewin and Mikenberg in [11], proving that they are all algebraizable in the sense of Blok and Pigozzi in [3] but not finitely algebraizable. A characterization of the finitely algebraizable logics defined by LPP-matrices is given.We also make an algebraic study of the equivalent algebraic semantics of the logics associated to the matrices ℳ32,2, ℳ32,1, ℳ31,1, ℳ31,3, and ℳ4 appearing in [11] proving that they are (...) not varieties and finding the free algebra over one generator. (shrink)

This paper analyzes the theory of area developed by Euclid in the Elements and its modern reinterpretation in Hilbert’s influential monograph Foundations of Geometry. Particular attention is bestowed upon the role that two specific principles play in these theories, namely the famous common notion 5 and the geometrical proposition known as De Zolt’s postulate. On the one hand, we argue that an adequate elucidation of how these two principles are conceptually related in the theories of Euclid and Hilbert is highly (...) relevant for a better understanding of the respective geometrical practices. On the other hand, we claim that these conceptual relations unveil interesting issues between the two main contemporary approaches to the study of area of plane rectilinear figures, i.e., the geometrical approach consisting in the geometrical theory of equivalence and the metrical approach based on the notion of measure of area. Finally, in an appendix logical relations among equivalence, comparison and addition of magnitudes are examined schematically in an abstract setting. (shrink)